Lettere - 30/03/2022
Can we trust trials with such features?
Possiamo fidarci di studi clinici con queste caratteristiche?
On 2 January 2020, the New England Journal of Medicine published an article by Amarenco et al. entitled ‘A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke’.1It is a parallel-group trial made in France and South Korea. The Authors “randomly assigned patients with ischemic stroke in the previous 3 months or a transient ischemic attack (TIA) within the previous 15 days to a target LDL cholesterol level of less than 70 mg per deciliter (lower-target group) or to a t…